2024 Spasticity Management 101 - Treatment Modalities-Chemodenervation

Chemodenervation - Botulinum Toxins

Video Transcription

Video Summary

In this video, Dr. Nicholas Godby discusses chemodenervation with botulinum toxin. He explains the mechanism of action and duration of the toxin, as well as the process of toxin preparation and dilution. He emphasizes the importance of individualizing dosing for each patient and starting with low doses. Risks of injection include diffusion from the intended site and unintended loss of function, but these effects are generally temporary. Dr. Godby also mentions the contraindications to chemodenervation with toxin and the equipment needed for injection. Overall, botulinum toxin achieves chemodenervation by preventing acetylcholine release and its effects are temporary.

Keywords

chemodenervation

botulinum toxin

dosing

contraindications

acetylcholine