Atypical Presentation of Weakness and Abnormal EMG Findings in a Patient with CML Due to ALS: A Case Report-Atypical Presentation of Weakness and Abnormal EMG Findings in a Patient with CML Due to ALS: A Case Report

Atypical Presentation of Weakness and Abnormal EMG Findings in a Patient with CML Due to ALS: A Case Report

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Video Summary

This video discusses a case report of a 35-year-old female who presented with weakness and abnormal EMG findings. She had a history of chronic myeloid leukemia (CML) and amyotrophic lateral sclerosis (ALS). The patient experienced muscle spasms and stiffness, which progressed to weakness in the left lower and upper extremities. MRI revealed non-specific lesions in the brain, and EMG showed motor neuron pathology but not specific to ALS. Sensory findings were also present, which are not typical of ALS. After ruling out other possible causes, the diagnosis of ALS was eventually made, possibly related to the underlying CML. It is important to consider ALS in patients with progressive weakness, even with inconclusive EMG studies.

Keywords

case report

weakness

EMG findings

amyotrophic lateral sclerosis

chronic myeloid leukemia