Management of Major PASC-Related System Disorders, Research, and the Future Goals for the AAPMR PASC Collaborative-Session Presentation

Video Transcription

Video Summary

In this video, the prevalence and manifestations of cognitive dysfunction in Post-Acute Sequelae of SARS-CoV-2 (PASC), also known as long COVID, are discussed. Studies indicate that cognitive dysfunction is a common symptom, with estimates ranging from 10% to 25% of PASC patients experiencing cognitive complaints. Memory and language problems are reported as the most common cognitive issues. However, cognitive function in PASC can also be affected in executive function, attention, processing speed, and memory. The underlying mechanisms for cognitive dysfunction in PASC are still being investigated, but potential factors include ongoing inflammation, vascular effects, neurologic effects, psychological factors, and the impact of hospitalization and critical illness. A comprehensive approach, including clinical history, cognitive assessments, neurologic examinations, and laboratory tests, is recommended for evaluating cognitive dysfunction in PASC. Treatment involves a multidisciplinary approach, including cognitive rehabilitation, psychological support, lifestyle modifications, and education on cognitive strategies. Ongoing support and monitoring are crucial for PASC patients with cognitive dysfunction.<br /><br />The video also addresses other aspects of long COVID, such as cardiac manifestations and exercise recommendations. Further research is needed to understand the underlying mechanisms of long COVID and develop effective treatments. Comprehensive assessments, including history, physical examination, and specific cognitive and cardiac tests, are essential for diagnosis and treatment planning. Lifestyle modifications, medications, and referrals to specialists are among the treatment strategies suggested. The challenges of managing long COVID in athletes and the impact of healthcare disparities on access to care are also discussed. Collaboration, patient involvement, and perspectives are emphasized as crucial in guiding future research and treatment approaches for long COVID.

Keywords

cognitive dysfunction

long COVID

prevalence

memory problems

executive function

underlying mechanisms

inflammation

treatment

lifestyle modifications

cardiac manifestations

research

diagnosis

collaboration