Metastatic Melanoma as a Rare Cause of Distal Lower Extremity Compartment Syndrome-Metastatic Melanoma as a Rare Cause of Distal Lower Extremity Compartment Syndrome

Metastatic Melanoma as a Rare Cause of Distal Lower Extremity Compartment Syndrome

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Video Summary

This case discusses a 57-year-old male with a history of melanoma who developed compartment syndrome due to metastatic melanoma in his right leg. The patient experienced pain, pressure, swelling, and impaired mobility. Initial treatment with Pembrolizumab did not alleviate symptoms, so a new chemotherapy regimen was started with Dibrafinib and Tremetinib. The patient also received physical rehabilitation, including medication for pain relief, a compression sleeve for swelling, and a foot drop orthosis brace. Subsequent imaging showed improvement in the size of the metastatic lesion and the patient's pain was well controlled. This case highlights the importance of considering neoplasia as a potential cause of compartment syndrome in patients with a history of malignancy.

Keywords

melanoma

compartment syndrome

metastatic melanoma

chemotherapy

physical rehabilitation