What's in a Watt: Implications for Cancer Rehabilitation-Session Presentation

Video Transcription

Video Summary

The video is a presentation given by Dr. Inigo San Milan and Dr. Adrian Christian on the Warburg effect in cancer metabolism and the use of exercise in cancer treatment. Dr. San Milan explains the role of lactate in cancer cells and how it can regulate gene expression and promote cancer growth. He also presents a methodology for measuring mitochondrial function and prescribing exercise for cancer patients. Dr. Christian emphasizes the importance of measuring leg power in cancer patients and how it can predict mortality and mobility limitations. He proposes a standardized approach for measuring leg power and setting cut-off values. The presentation highlights the potential of exercise as a therapeutic approach in cancer treatment. <br /><br />In addition, the video discusses a dashboard that tracks the physical function of cancer patients using self-reported and objective metrics. The dashboard includes various tests and measures such as physical function, fatigue, balance, and grip strength. It can be customized to suit the needs of clinicians and researchers and provides a bird's-eye view of physical function. The data collected can help identify changes in functional status and inform treatment plans. The dashboard has several advantages such as educating patients and clinicians, tracking changes over time, and identifying trends in physical function. However, there are limitations such as missing data and data integrity issues. The presenter mentions future developments including incorporating patient apps and musculoskeletal ultrasound measurements. The main message is that the dashboard can enhance the quality of life for cancer patients by monitoring and improving their physical function.

Keywords

Warburg effect

cancer metabolism

exercise in cancer treatment

lactate in cancer cells

gene expression regulation

mitochondrial function measurement

leg power measurement

mortality prediction

dashboard for tracking physical function

self-reported metrics

objective metrics

quality of life improvement